Gene and Protein Expression Changes in Human Trabecular Meshwork Cells Treated with Transforming Growth Factor-
نویسندگان
چکیده
METHODS. Human trabecular meshwork cells from five donors were cultured for 3 days with 1 ng/mL of either TGF1 or 2. Changes in gene expression determined with gene microarrays and alterations in protein expression detected by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ ionization-time-of-flight mass spectrometry (MALDI-TOF-MS) were studied in these cells after the incubation.
منابع مشابه
Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-beta.
PURPOSE To determine the genomic and proteomic expression changes in human trabecular meshwork cells when they are treated with transforming growth factor (TGF)-beta. METHODS Human trabecular meshwork cells from five donors were cultured for 3 days with 1 ng/mL of either TGF-beta1 or -beta2. Changes in gene expression determined with gene microarrays and alterations in protein expression dete...
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تاریخ انتشار 2004